People

Nadia obtained a B.A. in Molecular and Cellular Biology from U.C. Berkeley, and a Ph.D. from Harvard Medical School where she characterized T cell responses to the bacterium Chlamydia trachomatis in a mouse infection model. She then conducted a postdoctoral fellowship at the J. David Gladstone Institutes, where she identified factors in human seminal plasma that potently enhance HIV infection and studied their mechanism of action. Currently, her lab uses ex vivo tissue models and high-parameter single-cell analysis approaches to study HIV transmission and persistence, T cell immunity to SARS-CoV-2, and reproductive health. Nadia is a member of UCSF's AIDS Research Institute (ARI), Center for Reproductive Sciences (CRS), ImmunoX, and the Biomedical Sciences (BMS) graduate program. Outside the lab, Nadia enjoys the arts, being active, and traveling to faraway places.

Alicer obtained a B.S in Biology with a minor in French, followed by a Ph.D. in Infectious Diseases, from the University of Georgia. During her doctoral studies in the lab of Dr. Julie Moore, she investigated the crosstalk between inflammation, coagulation, and oxidative stress in murine models of placental malaria and using samples from endemic women. This research led to discovery of new therapeutic targets to improve negative pregnancy outcomes due to malaria infection. She has a strong interest in women’s health, and has served numerous leadership roles to promote diversity and equity in science. Alicer joined the Roan lab in 2023, and is characterizing HIV-specific T cell responses in people living with HIV, and endometrial immune responses in the context of infectious diseases and infertility. Outside the lab, Alicer is a self-proclaimed foodie, and enjoys traveling and learning different languages.

Ifeanyi Jude Ezeonwumelu obtained an M.Sc. in Forensic Sciences from the University of Lincoln (UK), Instituto Universitario Egas Moniz (Portugal), and the Universidad de Córdoba (Spain), all under an Erasmus Mundus scholarship. This was then followed by a PhD in the lab of Dr. Ester Ballana at the AIDS research institute at the Autonomous University of Barcelona (Spain). His prior research included phylogenetic studies of HIV transmission, as well as molecular epidemiology of viral epidemics including hepatitis viruses. His doctoral thesis work focused on characterizing novel innate immunomodulatory strategies to tackle HIV persistence. In 2023, Ifeanyi joined the Roan lab, where he will be using single-cell “omics” approaches to characterize the molecular signatures of cells persistently infected with HIV with the goal of developing novel strategies to target cells. Outside of the lab, Ifeanyi enjoys walking, hiking, dancing, and singing. His happy space is the kitchen - cooking delectable spicy meals.

Julie obtained a M.S in Cellular biology from University of Rennes. This was followed by an internship in the lab of Dr. Riteau at the University of Lyon 1 in France, where she studied how the Annexin-1 protein helps spreading Influenza virus infection. To deepen her background in virology, she started conducted a PhD at the IRSET Institute, in Rennes, under the supervision of Dr. Nathalie Dejucq-Rainsford. Her research focused on deciphering the mechanisms of transmigration of infected seminal leukocytes across the colorectal mucosa, and the modulatory effect of the seminal plasma on this transmission. She also worked on the phenotypical characterization of seminal leukocytes. In 2019, she joined the Roan lab where she will be working on using single-cell approaches to characterize cells productively- and latently-infected with HIV in different tissues. Outside the lab, Julie enjoys travelling around the world and discovering new places, spending some time with friends and family, and sports to clear her mind!

Ashley obtained a B.S. from Humboldt State University, where she majored in Biology with an emphasis in Cellular and Molecular Biology. This was followed by an internship sponsored by the California Institute for Regenerative Medicine (CIRM) in the lab of Dr. Linda Giudice at UCSF, studying human endometrial mesenchymal stem cells and endometriosis. She then obtained a Ph.D. from Rutgers University where she tested the lactocrine hypothesis for maternal programming of postnatal uterine development and adult endometrial function in pigs. In 2018, she joined the Roan lab, where she is using mass cytometry to characterize the molecular basis of intrinsic cellular permissivity of CD4+ T cells to HIV in the context of the restrictive or permissive environment of the female reproductive tract. Outside the lab, Ashley enjoys reading and spending time with friends and family.

Robin majored in Journalism and minored in English at the University of Texas at Arlington, and moved to San Francisco in 1993 from Dallas, Texas, where he was Executive Assistant to the Medical Director of the Dallas Psychiatric Intensive Care Unit. In Dallas, Robin also worked at the Oak Lawn Counseling Center, a non-profit organization whose mission was to serve the LGBT+ community. From 1998-2022, Robin supported Dr. Warner Greene at Gladstone. Currently, Robin provides administrative support to Drs. Nadia Roan and Jennifer Doudna and members of their research teams at Gladstone. Beginning in 1998, Robin frequently participated as a walker in the annual San Francisco AIDS Walk fundraiser. In 2018, he raised $1,525.00 thanks to the generosity of friends and colleagues, and estimates that over the past 24 years, he has raised ~$50,000 for this cause. When not working, Robin enjoys trips to Monterey Bay, Big Sur, and western Marin and Sonoma counties. Favorite pastimes include cooking and amateur photography.

Xiaoyu obtained a B.S. in Biotechnology from Sichuan University in China, and a PhD from the University of North Texas Health Science Center where she studied the HIV Nef protein and HIV latency in astrocytes in the lab of Dr. Johnny He. After graduation, she joined Dr. Warner Greene’s lab at Gladstone Institutes and conducted her postdoctoral fellowship studying HIV pathogenesis in tissue CD4+ T cells. In 2022, she joined the Roan lab as a staff research scientist, where she is using single cell multiomics technologies and computational approaches to characterize HIV reservoir cells and understand HIV persistence. Outside the lab, Xiaoyu is a digital drawing artist and plant lover. She also enjoys cooking, hiking, and traveling (especially in search of good food).

Tongcui obtained a M.S. in Biochemistry and Molecular Biology from Shantou University in China, and a Ph.D. from Wuhan University in China where she identified several naturally occurring anti-HIV products, including Soybean-derived Bowman-Birk Inhibitor and Kunitz Inhibitor. She then conducted a postdoctoral fellowship in the lab of Dr. Jianxin You at University of Pennsylvania, where she studied host immune responses to the tumorigenic DNA virus, Merkel cell polyomavirus (MCPyV), and how DNA viruses modulate host immune response to achieve latent infection. She then joined the Roan lab, where she is identifying biomarkers of HIV reservoir size and time-to-rebound during analytical treatment interruption (ATI). Outside of the lab, Tongcui enjoys traveling, being active and spending time with family.

Sophia obtained a B.S. in Biochemistry and a minor in Spanish from Beloit College in 2019. During her undergraduate studies abroad in Ecuador, she conducted research in the lab of Dr. Andres Caicedo where she analyzed the regenerative effects of artificial mitochondria transfer on UVR-damaged PBMCs. Upon graduating, she joined the Clinical Immunology team at Vir Biotechnology to characterize immune phenotypes of HBV+ patient serological samples and optimize PBMC isolation procedures for SARS-CoV2, HBV and HIV Phase II/III vaccine clinical trial samples. Her passion for women's health advocacy and interest in infectious diseases led her to join the Roan lab in 2023, where she aims to use CyTOF and single cell-sequencing to characterize HIV-infected cells, particularly from mucosal tissues including the female reproductive tract. When she is not in the lab, you can find her in the pottery studio, knitting, or hosting dinner parties with friends.

Jason obtained a B.A. from U.C. Santa Barbara, where he majored in Biochemistry and Molecular Biology. He conducted research in the Vaccines Department at Chiron, corp. (now Novartis, Inc) from 1990 to 2000, studying adjuvant formulations and vaccine candidates for herpesvirus. He then joined the lab of Dr. Warner Greene at the J. David Gladstone Institutes where he studied the viral determinants of HIV transmission. Since joining the Roan lab, he has been characterizing the phenotypic properties of genital mucosal cells and is using CyTOF to characterize the phenotypic properties of latent cells from the blood and tissues of HIV-infected individuals. Outside of the lab, Jason enjoys his wife's cooking. He also takes long, mushroom hunting walks with his son and appreciates the antics of Peppa Pig with his daughter.

Kailin obtained a B.S. from Peking University, where he majored in molecular biology and biochemistry. He then obtained a Ph.D. from Peking University in the lab of Dr. Wang Yuedan, where he studied tumor-associated antigens. He then conducted a postdoctoral fellowship in the lab of Dr. Chengqi Yi, during which he conducted research on RNA epigenetics. In 2020, he joined the lab of Dr. Wang Likun at the Institute of Biophysics researching endoplasmic reticulum stress using ribosome profiling. In 2021, he joined the Roan lab, where he will be characterizing immune responses to HIV and SARS-CoV-2. Outside the lab, Kailin enjoys playing badminton and computer games like Dota2.

Kyrlia received her B.A. in Biology, with a focus in Cell and Molecular Biology, at Occidental College in Los Angeles. During her undergraduate studies, she worked under Dr. Cheryl Okumura to develop a method to isolate and purify Group A Streptococcus-infected phagosomes in order to determine what proteins are associated with immune evasion and intracellular survival in macrophages. After graduating, she then joined Dr. Emily Goldberg's lab at UCSF and led a project investigating the mechanisms underlying oxidized low-density lipoprotein uptake and retention in neutrophils in the context of atherosclerosis. Since joining the Roan Lab in 2021, she has been working on research projects aimed to better understand the crosstalk between T cells and RNA viruses, and to identify signatures of inflammatory diseases affecting women. In her free time she enjoys cooking, baking (and especially eating) goods from new recipes, hiking, and traveling anywhere and everywhere.