Lab Overview & Research

Welcome!  We are interested in studying how cells and secretions of the mucosa, particularly the genital mucosa, can affect immunity, infection by HIV, and reproductive health in general. Our approaches include ex vivo tissue infection models, multi-parameter single-cell phenotyping (including both flow cytometry and mass cytometry), and global gene expression analysis. Our research is relevant for efforts to prevent HIV transmission and pathogenesis, and for efforts to obtain a better understanding of the molecular pathways in mucosal tissues that affect immunity and pathology.