Lab Overview & Research

Welcome! We are interested in studying how cells and soluble factors of lymphoid and mucosal tissues, including the genital mucosa and gut, can affect immunity, HIV infection and persistence, and reproductive health. Our main approaches include ex vivo tissue infection models and multi-parameter single-cell phenotyping analysis of datasets generated by flow cytometry, mass cytometry, and single-cell RNAseq. Our research is relevant for efforts to prevent HIV transmission and for developing an HIV cure, and for efforts to obtain a better understanding of the molecular pathways in mucosal tissues that affect immunity and pathology.